Publications

2024

  1. E.M. Grafil, P. De Jean, D.P.I. Capaldi, L.B. Skinner, L. Xing, A.S. Yu.  Evaluation of artificial intelligence and optical image recognition techniques used in OneIso, an off-axis Winston-Lutz quality assurance phantom.  Biomedical Physics & Engineering Express.  December 2024. doi.org/10.1088/2057-1976/ada037
  1. D.P.I. Capaldi, L.B. Skinner, D. Pinkham, S. Zavgorodni, O. Stafford, M. Shirmohammad, J.E. Matney, P. Dubrowski, P. De Jean, E.M. Grafil, A.S. Yu.  A multi-institutional trial evaluating the use of an integrated quality assurance phantom for frameless single-isocenter multitarget stereotactic radiosurgery.  Frontiers of Oncology.  October 2024. doi.org/10.3389/fonc.2024.1445166
  1. D.P.I. Capaldi*, J.Y. Wang*, V. Sheth, L. Liu, E.A. Kidd*, D.H. Hristov*.  PRM of IVIM MRI and PET in Locally Advanced Cervical Carcinoma undergoing Concurrent Chemoradiation Therapy.  Physics and Imaging in Radiation Oncology.  August 2024. doi.org/10.1016/j.phro.2024.100630 (* Equal Contribution).
  1. Y. Friedlander, S. Munidasa, N. Ragunayakam A. Thakar, C. Venegas, M. Kjarsgaard, B. Zanette, D.P.I. Capaldi, G. Santyr, P. Nair, S. Svenningsen. Phase-Resolved Functional Lung (PREFUL) MRI to Quantify Ventilation: Feasibility and Physiological Relevance in Severe Asthma.  Academic Radiology.  February 2024.  doi.org/10.1016/j.acra.2024.01.039
  1. M. Salans, L. Ni, O. Morin, B. Ziemer, D.P.I. Capaldi, D.R. Raleigh, H. Vasudevan, J. Chew, J. Nakamura, P.K. Sneed, L. Boreta, J. Villanueva-Meyer, P. Theodosopoulos, S. Braunstein.  Adverse radiation effect versus tumor progression following stereotactic radiosurgery for brain metastases: Implications of radiographic uncertainty.  Journal of Neuro-Oncology.  January 2024.  doi.org/10.1007/s11060-024-04578-6

2023

  1. D.P.I Capaldi, M. Axente, A. Yu, N. Prionas, E. Hirata, T. Nano. A Couch Mounted Smartphone-based Motion Monitoring System for Radiation Therapy.  Practical Radiation Oncology.  December 2023.  doi.org/10.1016/j.prro.2023.11.013  ***This manuscript was featured on the cover of the journal (March-April 2024)***
  1. D.P.I. Capaldi, N.B. Konyer, M. Kjarsgaard, A. Dvorkin-Gheva, R.J. Dandurand, P. Nair, S. Svenningsen. Specific ventilation in severe asthma evaluated by non-contrast tidal breathing 1H MRI.  Radiology – Cardiothoracic Imaging. December 2023.  doi.org/10.1148/ryct.230054 ***This manuscript was editorialized doi.org/10.1148/ryct.230372 (December 2023) and invited to interview on RSNA podcast rsnaradiologycti.libsyn.com/specific-ventilation-in-severe-asthma***
  1. D.P.I Capaldi, C. Gibson, A. Villa, J.B. Schulz, B.P. Ziemer, J. Fu, P. Dubrowski, A.S. Yu, S. Fogh, J. Chew, L. Boreta, S.E. Braunstein, A. Witztum, E. Hirata, O. Morin, L.B. Skinner, T. Nano. Tungsten filled 3D printed lung blocks for total body irradiation.  Practical Radiation Oncology.  November 2023.  doi.org/10.1016/j.prro.2023.11.003. ***This manuscript was invited to interview for a Quicktakes: Practical Radiation Oncology, ASTRO, practicalradonc.org/video-do/tungsten-filled-3-dimensional-printed-lung-blocks-total-body-irradiation***

2022

  1. M. Sharma, P. Wyszkiewicz, V. Desaigoudar, F. Guo, D.P.I. Capaldi, G. Parraga. Quantification of Pulmonary Functional MRI: State-of-the-Art and Emerging Image Processing Methods and Measurements.  Physics in Medicine and Biology.  September 2022.  doi.org/10.1088/1361-6560/ac9510
  1. L. Shen, W. Zhao, D.P.I. Capaldi, J. Pauly, L. Xing.  A geometry-informed deep learning framework for ultra-sparse 3D tomographic image reconstruction. Computers in Biology and Medicine.  June 2022.  doi.org/10.1016/j.compbiomed.2022.105710
  1. B.P. Yaremko, D.P.I. Capaldi, K. Sheikh, D.A. Palma, A. Warner, A.R. Dar, E. Yu, G.B. Rodrigues, A. Louie, M. Landis, M. Sanatani, M.D. Vincent, J. Younus, S. Kuruvilla, J. Chen, A. Erickson, S. Gaede, G. Parraga, D.A. Hoover. Functional Lung Avoidance for Individualized Radiotherapy (FLAIR): Results of a Double-Blind, Randomized Controlled Trial.  International Journal of Radiation Oncology, Biology, Physics.  May 2022. doi.org/10.1016/j.ijrobp.2022.04.047
  1. E. Simiele*, D.P.I Capaldi*, D. Breitkreutz, B. Han, T. Yeung, J. White, D. Zaks, M. Owens, S. Maganti, L. Xing, M. Surucu, N. Kovalchuk.  Treatment planning system commissioning of the first clinical biology-guided radiotherapy machine.  Journal of Applied Clinical Medical Physics. May 2022. doi.org/10.1002/acm2.13638 (* Co-first Author)
  1. D. Pham, E. Simiele, D. Breitkreutz, D.P.I. Capaldi, O.M. Oderinde, L. Vitzthum, M. Gensheimer, B. Han, M. Surucu, D. Chang, N. Kovalchuk.  IMRT Treatment Planning Study for the First Clinical Biology-Guided Radiotherapy System.  Technology in Cancer Research & Treatment. May 2022. doi.org/10.1177/15330338221100231
  1. B. Han, D.P.I Capaldi, N. Kovalchuk, E. Simiele, J. White, D. Zaks, L. Xing, M. Surucu.  Beam Commissioning of the First Clinical Biology-Guided Radiotherapy System.  Journal of Applied Clinical Medical Physics. April 2022.  doi.org/10.1002/acm2.13607

2021

  1. Q.H. Sodji, R. Ko, R. Eyben, S.G. Owen, D.P.I. Capaldi, K. Bush, M. Binkley, F. Alrowais, B. Pickthorn, P.G. Maxim, M. Gensheimer, M. Diehn, B.W. Loo Jr.  Acute and Late Esophageal Toxicity Following Stereotactic Ablative Radiotherapy to Thoracic Tumors Near or Abutting the Esophagus.  International Journal of Radiation Oncology, Biology, Physics.  December 2021.  doi.org/10.1016/j.ijrobp.2021.12.008
  1. F. Guo, D.P.I. Capaldi, D.G. McCormack, A. Fenster, G. Parraga.  Ultra-short Echo-time Magnetic Resonance Imaging Lung Segmentation with Under-Annotations and Domain Shift.  Medical Image Analysis. June 2021. doi.org/10.1016/j.media.2021.102107
  1. D.P.I. Capaldi, L. Skinner, P. Dubrowski, H. Zhang, L. Xing, C.F. Chuang B.W. Loo, K. Bush, B. Fahimian, A. Yu.  A Robotically Assisted 3D Printed Quality Assurance Lung Phantom for Calypso.  Physics in Medicine and Biology.  March 2021.  doi.org/10.1088/1361-6560/abebaa. ***This manuscript is in the special issue: Focus on Early Career Researchers in Physics in Medicine and Biology***
  1. H. Zhang, D.P.I. Capaldi, D. Zeng, J. Ma, L. Xing.  Prior-image-based CT reconstruction using attenuation mismatched prior.  Physics in Medicine and Biology.  February 2021.  doi.org/10.1088/1361-6560/abe760  ***This manuscript is in the special issue: Focus on Early Career Researchers in Physics in Medicine and Biology***

2020

  1. D.P.I. Capaldi*, F. Guo*, L. Xing, G. Parraga.  Pulmonary Ventilation Maps generated using Free-breathing Proton MRI and a Deep Convolutional Neural Network.  Radiology. December 2020.  doi.org/10.1148/radiol.2020202861 ***This manuscript was editorialized doi.org/10.1148/radiol.2020204069 (December 2020)*** (* Co-first Author)
  1. E. Simiele, D. Breitkreutz, D.P.I. Capaldi, W. Liu, K. Bush, L.B. Skinner.  Precision radiotherapy via monochromatic Inverse Compton x-ray sources.  Medical Physics. October 2020.  doi.org/10.1002/mp.14552
  1. T.F. Nano, D.P.I. Capaldi, T. Yeung, C.F. Chuang, L. Wang, M. Descovich.  Technical Note: Performance of CyberKnife Tracking Using Low-Dose CT and kV Imaging.  Medical Physics.  October 2020.  doi.org/10.1002/mp.14537
  1. D.P.I. Capaldi, T.F. Nano, H. Zhang, L.B. Skinner, L. Xing.  Technical Note: Evaluation of Audiovisual Biofeedback Smartphone Application for Respiratory Monitoring in Radiation Oncology.  Medical Physics. September 2020.  doi.org/10.1002/mp.14484
  1. D.P.I. Capaldi*, L.B. Skinner*, P. Dubrowski, A.S. Yu.  An Integrated Quality Assurance Phantom for Frameless Single-isocenter Multitarget Stereotactic Radiosurgery.  Physics in Medicine and Biology. April 2020.  doi.org/10.1088/1361-6560/ab8534 (* Co-first Author)
  1. D.P.I. Capaldi, D.H. Hristov*, E.A. Kidd*.  Parametric Response Mapping of Co-registered Positron Emission Tomography and Dynamic Contrast Enhanced Computed Tomography to Identify Radio-resistant Sub-volumes in Locally Advanced Cervical Cancer.  International Journal of Radiation Oncology, Biology, Physics.  March 2020.  doi.org/10.1016/j.ijrobp.2020.03.023 (* Co-senior Author)
  1. J.L. MacNeil, D.P.I. Capaldi, A. Westcott, R.L. Eddy, A.L. Barker, D.G. McCormack, M. Kirby, G. Parraga.  Multi-Parametric Response Maps: Pulmonary Imaging Phenotypes of Chronic Obstructive Pulmonary Disease.  Radiology. February 2020. doi.org/10.1148/radiol.2020191735

2019

  1. A. Westcott, D.P.I. Capaldi, D.G. McCormack, A. Fenster, G. Parraga.  Chronic Obstructive Pulmonary Disease: CT Texture Analysis and Machine Learning to Predict Pulmonary Ventilation.  Radiology. November 2019.  doi.org/10.1148/radiol.2019190450 ***This manuscript was editorialized doi.org/10.1148/radiol.2019192162 (December 2019)***
  1. Y. Wu, Y. Ma, D.P.I. Capaldi, J. Liu, W. Zhao, J. Du, L. Xing.  Incorporating Prior Knowledge via Volumetric Deep Residual Network to Optimize the Reconstruction of Sparsely Sampled MRI.  Magnetic Resonance Imaging. March 2019.  doi.org/10.1016/j.mri.2019.03.012
  1. S. Svenningsen, E. Haider, C. Boylan, M. Mukherjee, R.L. Eddy, D.P.I. Capaldi, G. Parraga, P. Nair.  CT and functional MRI to evaluate airway mucus in severe asthma.  Chest. March 2019. doi.org/10.1016/j.chest.2019.02.403

2018

  1. F. Guo, D.P.I. Capaldi, D.G. McCormack, A. Fenster, G. Parraga.  A Framework for Fourier-Decomposition Free-Breathing Pulmonary 1H MRI Ventilation Measurements.  Magnetic Resonance in Medicine.  October 2018.  doi.org/10.1002/mrm.27527
  1. F. Guo, D.P.I. Capaldi, M. Kirby, K. Sheikh, S. Svenningsen, D.G. McCormack, A. Fenster, G. Parraga.  Development of a pulmonary imaging biomarker pipeline for phenotyping of chronic lung disease.  Journal of Medical Imaging.  April 2018.  doi.org/10.1117/1.JMI.5.2.026002
  1. A. Westcott, D.P.I. Capaldi, A. Ouriadov, D.G. McCormack, G. Parraga.  Hyperpolarized 3He MRI Ventilatory Apparent Diffusion Coefficient of Alpha-1 Antitrypsin Deficiency.  Journal of Magnetic Resonance Imaging.  August 2018.  doi.org/10.1002/jmri.26202
  1. D.P.I. Capaldi, R.L. Eddy, S. Svenningsen, F. Guo, J.S.H. Baxter, A.J. McLeod, P. Nair, D.G. McCormack, G. Parraga, CRRN Investigators.  Free-breathing Pulmonary MR Imaging to Quantify Regional Ventilation.  Radiology.  May 2018.  doi.org/10.1148/radiol.2018171993

2017

  1. C.J. Adams*, D.P.I. Capaldi*, R. Di Cesare, D.G. McCormack, G. Parraga, CRRN Investigators. On the potential role of MRI Biomarkers of COPD to Guide Bronchoscopic Lung Volume Reduction. Academic Radiology.  October 2017.  doi.org/10.1016/j.acra.2017.08.010 (* Co-first Author)
  1. D.P.I. Capaldi, G. Parraga.  Through the Looking Glass and What was Found There: More Imaging Biomarkers of COPD.  American Journal of Respiratory and Critical Care Medicine.  August 2017.  doi.org/10.1164/rccm.201707-1473ED
  1. D.P.I. Capaldi, K. Sheikh, R.L. Eddy, F. Guo, S. Svenningsen, P. Nair, D.G. McCormack, G. Parraga.  Free-breathing Pulmonary MRI Ventilation Response to Bronchodilator and Provocation in Severe Asthma.  Academic Radiology.  May 2017.  doi.org/10.1016/j.acra.2017.04.012
  1. F. Guo, S. Svenningsen, M. Kirby, D.P.I. Capaldi, K. Sheikh, A. Fenster, G. Parraga.  Thoracic CT-MRI Co-Registration for Regional Pulmonary Structure-Function Measurements of Obstructive Lung Disease.  Medical Physics.  February 2017.  doi.org/10.1002/mp.12160.  ***This manuscript was featured on the cover of the journal (May 2017)***
  1. A. Dasgupta, M. Kjarsgaard, D.P.I. Capaldi, K. Radford, F. Aleman, C. Boylan, L.C. Altman, T. Wight, G. Parraga, P.M. O’Byrne, P. Nair.  A pilot randomized clinical trial of mepolizumab in COPD with eosinophilic bronchitis. European Respiratory Journal. March 2017. doi.org/10.1183/13993003.02486-2016

2016

  1. K. Sheikh, F. Guo, D.P.I Capaldi, A. Ouriadov, R.L. Eddy, S. Svenningsen, G. Parraga, CRRN Investigators.  Ultra-short Echo Time Magnetic Resonance Imaging Biomarkers of Asthma. Journal of Magnetic Resonance Imaging. October 2016. doi.org/10.1002/jmri.25503
  1. F. Guo, S. Svenningsen, R.L. Eddy, D.P.I. Capaldi, K. Sheikh, A. Fenster, G. Parraga.  Anatomical pulmonary magnetic resonance imaging segmentation for regional structure‐function measurements of asthma.  Medical Physics.  May 2016.  doi.org/10.1118/1.4948999
  1. D.P.I. Capaldi, F. Guo, G. Parraga.  Imaging How and Where We Breathe Oxygen: Another Big Short?  Journal of Thoracic Disease.  March 2016.  doi.org/10.21037/jtd.2016.01.83
  1. N. Zha, D. Pike, S. Svenningsen, D.P.I. Capaldi, D.G. McCormack, G. Parraga.  Second-Order Texture Measurements of 3He Ventilation MRI: Proof of Concept Evaluation of Asthma Bronchodilator Response.  Academic Radiology.  February 2016.  doi.org/10.1016/j.acra.2015.10.010
  1. D.P.I. Capaldi, N. Zha, F. Guo, D. Pike, D.G. McCormack, M. Kirby, G. Parraga.  Pulmonary Imaging Biomarkers of Gas Trapping and Emphysema in COPD: 3He MR Imaging and CT Parametric Response Maps.  Radiology.  January 2016.  doi.org/10.1148/radiol.2015151484.  ***This manuscript was featured on the cover of the journal (May 2016)***
  1. D. Pike, M. Kirby, R.L. Eddy, F. Guo, D.P.I. Capaldi, A. Ouriadov, D.G. McCormack, G. Parraga.  Regional Heterogeneity of Chronic Obstructive Pulmonary Disease Phenotypes: Pulmonary 3He Magnetic Resonance Imaging and Computed Tomography.  Journal of Chronic Obstructive Pulmonary Disease.  January 2016. doi.org/10.3109/15412555.2015.1123682

2015

  1. K. Sheikh*, D.P.I. Capaldi*, D.A. Hoover, G. Parraga, D.A. Palma, B.P. Yaremko.  Magnetic resonance imaging biomarkers of chronic obstructive pulmonary disease prior to radiation therapy for non-small cell lung cancer.  European Journal of Radiology Open.  December 2015.  doi.org/10.1016/j.ejro.2015.05.003 (* Co-first Author)
  1. F. Guo, J. Yuan, M. Rajchl, S. Svenningsen, D.P.I. Capaldi, K. Sheikh, A. Fenster, G. Parraga.  Globally Optimal Joint Segmentation of Three-dimensional Pulmonary 1H and Hyperpolarized 3He MRI with Spatial Consistence Prior.  Medical Image Analysis.  July 2015.  doi.org/10.1016/j.media.2015.04.001
  1. D.P.I. Capaldi, K. Sheikh, F. Guo, S. Svenningsen, R. Etemad-Rezai, H.O. Coxson, J. Leipsic, D.G. McCormack, G. Parraga.  Free-breathing Pulmonary 1H and Hyperpolarized 3He MRI: Comparison in COPD and Bronchiectasis.  Academic Radiology. March 2015. doi.org/10.1016/j.acra.2014.10.003
  1. M. Bhuiyan, E.V. Malyarenko, M.A. Pantea, D.P.I. Capaldi, A.E. Baylor, R.G. Maev.  Time-Frequency Analysis of Clinical Percussion Signals using Matrix Pencil Method.  Journal of Electrical and Computer Engineering.  January 2015.  doi.org/10.1155/2015/274541

2014

  1. D.A. Hoover, D.P.I. Capaldi, K. Sheikh, D.A. Palma, G.B. Rodrigues, R. Dar, E. Yu, B. Dingle, M. Landis, W. Kocha, M. Sanatani, M. Vincent, J. Younus, S. Gaede, G. Parraga, B.P. Yaremko.  Functional lung avoidance for individualized radiotherapy (FLAIR): Study protocol for a randomized, double-blind clinical trial.  BMC Cancer.  December 2014.  doi.org/10.1186/1471-2407-14-934